On this page we provide links to some of the latest methodology research articles in prognosis and prediction research.

Please contact us about methods articles to add, as we want to be inclusive.

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2021

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• Minimum sample size for external validation of a clinical prediction model with a binary outcome (in-press, Stat Med)

• External validation of clinical prediction models: simulation-based sample size calculations were more reliable ... (PDF)

• A note on estimating the Cox‐Snell R2 from a reported C statistic (AUROC) to inform sample size calculations for developing a prediction model with a binary outcome (PDF)

• Clinical prediction models to predict the risk of multiple binary outcomes: a comparison of approaches (PDF)

• Adaptive sample size determination for the development of clinical prediction models (PDF)

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2020

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• Minimum sample size for external validation of a clinical prediction model with a continuous outcome (PDF)

• Calculating the sample size required for developing a clinical prediction model (PDF)

• Penalization and shrinkage methods produced unreliable clinical prediction models ...  (PDF) 

• Regression shrinkage methods for clinical prediction models do not guarantee improved performance (PDF)

• IPD meta‐analysis to examine interactions between treatment effect and participant‐level covariates (PDF)

• Temporal recalibration for improving prognostic model development and risk predictions ... (PDF)

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